MALDI-TOF MS is a widely used technology for glycan analysis because of its high throughput, automation possibilities, soft ionization, low sample consumption, and excellent speed. Thanks to this technique, Creative Biolabs can provide clients worldwide with a large array of glycoprotein analysis services that are both high-quality and reasonably priced.
Analysis of Glycoproteins Using MALDI-TOF Mass Spectrometry
The mass spectrometry method known as MALDI-TOF MS has been used extensively in biopharmaceutical glycoanalysis for many years. The latest generation of MALDI mass spectrometers is capable of precisely identifying the masses of glycans, proteins, and peptides. It can also segment these materials to extract sequence information for proteins or polypeptides.
The soft ionization technique known as MALDI was created to ionize relatively big polypeptides and proteins, but it has now been extended to ionize complex polysaccharides, oligonucleotides, and glycoproteins. One benefit of MALDI-TOF MS is that the analytes are nearly never fragmented during the soft ionization process, allowing for the identification of the analytes' molecule ions even when the mixture is present.
